News

We contributed to work led by Melissa Harrison's lab (U. Wisconsin) on understanding how GAF foci are formed: https://www.biorxiv.org/content/10.1101/2022.11.29.518380v1

Kaeli won both the best application and peoples choice awards at the CCGM retreat!

Highlights this year included "Drosop-Leia" and "Polycomb-repressed graduate student"

A pleasure to contribute to this work spearheaded by our close collaborators in Liling Wan's lab. Read the paper here. co-authors from our lab are Alan Boka and Kaeli Mathias.

Sena Sarıkaya (DSRB) is doing her 1st rotation with us. She wants to push the limits of in vivo imaging!

Santosh Adhikari joins the lab as a postdoc, He just completed his PhD in physics from U. of Minnesota.

Mattisen Dimler joined us a research technician, she will be supporting the labs mission and learning to do research.

Gabriela Hayward-Lara joined the lab after rotating with us last fall. We are very excited to have her on board. 

Anna Crombie, a student at the University of Leicester has joined us for an internship this summer

Alan Boka was selected to be on the Structural Biology and Molecular Biophysics training grant!

Sapna Krishnakumar, a sophomore in Biological Sciences at IISER Mohali has joined us for an internship this summer

Our team "MS2 good to lose!" (named by S Fallacaro) won the lab Olympics at the CDB Retreat! 

Congratulations Alan Boka on becoming our second PhD Candidate! 

Congratulations Kaeli Mathias on becoming our first PhD Candidate! 

S returned to our lab for their PhD after rotating with us last summer. They will be working on questions related to the mechanotransduction of gene regulation

Ernesto is a sophomore majoring in Biology at UPenn and has a keen interest in embryonic development!

​

Our research was featured in the CHOP cornerstone blog: https://www.research.chop.edu/cornerstone-blog/new-innovator-award-advances-live-imaging-technology-to-see-embryonic-gene-regulation

We received and installed our new Femtojet microinjection system and our new Lecia DMi8 inverted microscope. Lots of poking embryos coming up!

-

As our light-sheet microscope is near ready for prime time we had an all hands on deck effort to install a enclosure to protect the optics and shield the instrument form air currents in the room!

Al l the major components of our MOSAIC microscope are finally in place and now its time for fine-tuning!

Sarah is a freshman majoring in Biochemistry at UPenn. She comes to our lab through the Penn Freshmen Exposure to Research in Biological Science (PennFERBS) and we are very happy to have her start her scientific career with us!

We celebrated Halloween with a "meet and treat" with the whole CHOP CCGM! Fun and silly festivities ensued. 

We celebrated getting the NIH New Innovator award with our close collaborators and fellow awardee Liling Wan and her lab. Our co-mentored student Kaeli Mathias is guaranteed/mandated to have a super innovative thesis project! 

The lab was awarded a NIH Directors New Innovator Award (DP2). This $2.4 million award will fund our efforts to develop new approaches to quantify the molecular dynamics of gene expression and nuclear organization during early embryonic development.
NIH Press Release | Awardees | CHOP Press Release | Penn Press Release

We are very happy to have Net on board. Net brings with him tons of experience working with flies and lots of enthusiasm. He has previously worked as a Research Technician with Shawn Little at Penn and Thomas Gregor at Princeton. 

Gabriella Hayward Lara who is in the DSRB program and recently graduated from Princeton joins the lab for her first rotation. Welcome!

We celebrated the end of summer rotations and welcomed some new folks on a beautiful Philly day!

We kicked off our image processing workshop series. We discuss how to write code to analyze imaging data quantitatively while minimizing manual intervention. This workshop is led by Alan Boka and Tomer Lapidot (Ophir Shalem's lab).

Congratulations to Kaeli Mathias for being selected for the Genetics T32 grant. lots of exciting discoveries ahead!

Cody Eskandarian  is an undergraduate in biochemistry and biophysics at UPenn.

We received our second optical table (thanks Melike Lakadamyali's lab), nothing like the feeling of putting the first piece on a blank optical table. We will be using this one for prototyping new optical setups.  

We celebrated the end of Kaeli Mathias's and Adam Jabak's rotations and welcome Guzel and Patrick with libations and games at "The Commons" 

Guzel Naik is joining us for 6 months as a research intern. He has a BSc in Biology and previous research experience in epigenetics at the Lahore University of Management Sciences

Patrick Samaha joins us for the summer. He is currently an undergraduate student in Bioengineering at the University of Toronto.

S Fallacaro joins the lab for their first rotation. They are a student in The Developmental, Stem Cell, and Regenerative Biology division within the Cell and Molecular Biology graduate group. 

I think he may need a ladder soon

Kaeli Mathias decides to be co-mentored by Mustafa and Dr. Liling Wan. She has boundless enthusiasm, energy, and deep curiosity! 

The lab surprised Mustafa with a birthday cake. What a great group of people! :)

Its growing!

Super excited that Alan Boka has decided to join the lab for his PhD work. He is a fantastic young scientist with a fearless attitude. Looking forward to lots of creating and exciting science.

Good progress for one day! After receiving our room we have our optical table, two photon laser, and server rack setup!

The renovation of our microscope room is  complete. After 5 months of anticipation we can finally start on our microscope. Thanks to CHOP for facilitating this large rennovation

Read the feature here: https://cambnewsletter.wixsite.com/blog/single-post/pioneering-pandemic-pis

Kaeli Mathias and Adam Jabak from the BMB graduate group joined the lab for their third rotations.  The flies still outnumber us significantly.

Weather was warm, vaccines were in arms and our first rotation student Alan Boka's time was up. We had a cookout and some libations to celebrate!

Its so pretty!

Looking forward to lots of photons

We ran a gel and learned something. Science!

And we are off! first group meeting.

Today we welcome our first postdoc Apratim Mukherjee who is a mechanical engineering PhD from Virginia Tech where he studied how cells sense their extracellular matrix using synthetic nanofiber networks. We also welcome Alan Boka a rotation student from BMB Graduate Group. The lab is growing!

Today our environmental chambers to house our flies from Darwin Chambers were installed. Now they have a nice cozy place to grow!

Watch a video of the installation here: https://twitter.com/MustafaMir16/status/1352214822830669826?s=20

We are a "we" now. Our first lab member Nick Gattone has joined us as the labs first Technician! Nick has just finished his Masters working with Nir Yakoby at Rutgers where he worked on the role of tRNA fragments in regulating gene expression. Welcome Nick!

The lab is officially open!